Biological mechanism of sex difference in stroke manifestation and outcomes.
Wi-Sun RyuJinyong ChungDawid SchellingerhoutSang-Wuk JeongHang-Rai KimJung E ParkBeom Joon KimJoon-Tae KimKeun-Sik HongKyung Bok LeeTai Hwan ParkSang-Soon ParkJong-Moo ParkKyusik KangYong-Jin ChoHong-Kyun ParkByung-Chul LeeKyung Ho YuMi Sun OhSoo Joo LeeJae Guk KimJae-Kwan ChaDae-Hyun KimJun LeeMoon-Ku HanMan Seok ParkKang-Ho ChoiJuneyoung LeeHee Joon BaeDong-Eog KimPublished in: Neurology (2023)
Female patients have more frequent middle cerebral artery disease and striatocapsular motor-pathway involvement with acute ischemic stroke, along with left parieto-occipital cortical infarcts showing greater severity for equivalent infarct volumes than in male patients. This leads to more severe initial neurological symptoms, higher susceptibility to neurological worsening, and less 3-month functional independence, when compared with male patients.
Keyphrases
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- acute ischemic stroke
- middle cerebral artery
- prognostic factors
- physical activity
- metabolic syndrome
- skeletal muscle
- heart failure
- coronary artery disease
- acute coronary syndrome
- blood brain barrier
- weight loss
- internal carotid artery