SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells.

Camilla AnastasioIsabella DonisiVitale Del VecchioAntonino CollocaLuigi MeleCelestino SarduRaffaele MarfellaMaria Luisa BalestrieriNunzia D'Onofrio

Published in: Cellular & molecular biology letters (2024)

These results deepened knowledge on the iSGLT2 contribution in limiting CRC tumorigenesis unveiling the SGLT2/SIRT3 axis in the cytotoxic mechanisms.

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