Homocysteine-induced decrease in HUVEC cells' resistance to oxidative stress is mediated by Akt-dependent changes in iron metabolism.

Andżelika BorkowskaWieslaw ZiolkowskiKatarzyna KaczorAnna Herman-AntosiewiczNarcyz KnapAgata WronskaJędrzej Antosiewicz

Published in: European journal of nutrition (2020)

These data indicate that Hcy induces an increase in cellular ferritin level, and the process is mediated by alterations in Akt-FOXO3a signaling pathway.

Keyphrases

signaling pathway
induced apoptosis
pi k akt
oxidative stress
cell cycle arrest
diabetic rats
epithelial mesenchymal transition
high glucose
electronic health record
dna damage
big data
iron deficiency
transcription factor
deep learning
machine learning