Drug susceptibility profiling and genetic determinants of drug resistance in Mycobacterium simiae isolates obtained from regional tuberculosis reference laboratories of Iran.

Sara DaneshfarAzar Dokht Khosravi Aram Asareh Zadegan Dezfuli

Published in: PloS one (2022)

This study revealed amikacin, clarithromycin, and moxifloxacin as the most effective antibiotics. However, since M. simiae exhibited a high level of antibiotic resistance in vitro, therefore, species identification and determining the antibiotic susceptibility pattern of the isolates are essential before treatment.

Keyphrases

mycobacterium tuberculosis
genetic diversity
single cell
helicobacter pylori
genome wide
pulmonary tuberculosis
gene expression
copy number
human immunodeficiency virus
drug induced
bioinformatics analysis