Shunt occlusion prior to lenvatinib administration prevents hepatic encephalopathy and hyperammonemia.

Ai KuwaharaRyu SasakiMasanori FukushimaMasafumi HaraguchiSatoshi MiumaHisamitsu MiyaakiKazuhiko Nakao

Published in: JGH open : an open access journal of gastroenterology and hepatology (2020)

Shunt occlusion prior to lenvatinib administration prevented hyperammonemia and hepatic encephalopathy. Shunt occlusion may be an effective treatment option to administer molecular target agents in patients with portosystemic shunts.

Keyphrases

pulmonary artery
early onset
coronary artery
pulmonary hypertension
mouse model
pulmonary arterial hypertension
single molecule