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Immunogenicity and contraceptive efficacy of recombinant fusion protein encompassing Sp17 spermatozoa-specific protein and GnRH: Relevance of adjuvants and microparticles based delivery to minimize number of injections.

Vidisha MinhasRobin KumarTrisha MoitraRita SinghAmulya K PandaSatish Kumar Gupta
Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2020)
Single-dose immunization with PLA-MPs entrapping Sp17C -GnRH2 along with soluble recombinant protein in alum generated long-lasting infertility in female mice.
Keyphrases
  • protein protein
  • amino acid
  • cell free
  • binding protein
  • high fat diet induced
  • adipose tissue
  • metabolic syndrome
  • polycystic ovary syndrome
  • platelet rich plasma
  • insulin resistance
  • wild type