Antimicrobial therapy utilization in neonates with hypoxic-ischemic encephalopathy (HIE): a report from the Children's Hospital Neonatal Database (CHND).

Rakesh RaoKyong-Soon LeeIsabella ZanilettiToby D YanowitzRobert DiGeronimoMaria L V DizonShannon E HamrickGirija NatarajanEric S PeeplesKarna MurthyAmit M MathurAn Massaro

Published in: Journal of perinatology : official journal of the California Perinatal Association (2019)

Incidence of early confirmed infection in neonates with HIE/TH (23/1000) is significantly higher than reported rates of early onset sepsis in term and near term infants (0.5-1.0/1000 live births). Antimicrobial-stewardship opportunities exist in infants with negative cultures.

Keyphrases

early onset
gestational age
preterm infants
low birth weight
late onset
preterm birth
adverse drug
young adults
staphylococcus aureus
intensive care unit
healthcare
risk factors
acute kidney injury
septic shock
stem cells
mesenchymal stem cells
smoking cessation
replacement therapy