Accurate prostate cancer detection based on enrichment and characterization of prostate cancer specific circulating tumor cells.

Sewanti LimayeSimon ChowdhuryNitesh RohatgiAnantbhushan RanadeNelofer SyedJohann RiedemannDarshana PatilDadasaheb AkolkarVineet DattaShoeb PatelRohit ChougulePradyumna ShejwalkarKiran BendaleSachin ApurwaStefan SchusterJinumary JohnAjay SrinivasanRajan Datar

Published in: Cancer medicine (2023)

The test accurately detects PrAD-CTCs with high sensitivity and specificity irrespective of stage, serum PSA or Gleason score, which translates into low risks of false negatives or overdiagnosis. The high accuracy of the test could offer advantages over PSA based prostate cancer detection.

Keyphrases

prostate cancer
circulating tumor cells
radical prostatectomy
loop mediated isothermal amplification
real time pcr
label free
high resolution
quantum dots