Invariant natural killer T cells and incidence of first-time coronary events: a nested case-control study.
Lukas TomasPernilla KatraWiaam BadnLinda AnderssonJan NillsonAlexandru SchiopuDaniel EngelbertsenIsabel GonçalvesEva BengtssonHarry BjörkbackaPublished in: European heart journal open (2023)
Our findings indicate that animal studies suggesting an atherosclerosis-promoting role for iNKT cells may not translate to human cardiovascular disease as our data show an association between high circulating numbers of DN iNKT cells and decreased risk of incident CE.
Keyphrases
- cardiovascular disease
- induced apoptosis
- cell cycle arrest
- endothelial cells
- coronary artery disease
- coronary artery
- type diabetes
- endoplasmic reticulum stress
- cell death
- oxidative stress
- case control
- electronic health record
- risk factors
- machine learning
- metabolic syndrome
- left ventricular
- heart failure
- induced pluripotent stem cells
- cell proliferation
- energy transfer
- aortic valve
- cardiovascular risk factors
- ejection fraction
- artificial intelligence
- deep learning