Comparison of HER2-Targeted Antibodies for Fluorescence-Guided Surgery in Breast Cancer.

Solmaz AghaAmiriJo SimienAlastair M ThompsonJulie VossSukhen C Ghosh Servando Hernandez Vargas Sarah Kim Ali Azhdarinia Hop S Tran Cao

Published in: Molecular imaging (2021)

We showed for the first time that fluorescent trastuzumab and pertuzumab immunoconjugates have similar NIRF imaging performance and demonstrated the possibility of performing HER2-targeted FGS with agents that possess distinct epitope specificity.

Keyphrases

epidermal growth factor receptor
cancer therapy
minimally invasive
metastatic breast cancer
high resolution
coronary artery bypass
quantum dots
single molecule
living cells
drug delivery
energy transfer
mass spectrometry
coronary artery disease
photodynamic therapy
fluorescence imaging