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A Finite Element Investigation on Material and Design Parameters of Ventricular Septal Defect Occluder Devices.

Zhuo ZhangYan XiongJinpeng HuXuying GuoXianchun XuJuan ChenYun-Bing WangChen Yu
Published in: Journal of functional biomaterials (2022)
The experimental testing presented in the study showed that the mechanical performance of the Nitinol occluder and the MARF prove that it has sufficient ability to resist falling out from its intended placement. This study also represents the first experimentally validated computational model of braided occluders, and provides a perception of the influence of geometrical and material parameters in these systems. The results could further provide meaningful suggestions for the design of biodegradable VSD closure devices and to realize a series of applications for biodegradable materials in VSD.
Keyphrases
  • drug delivery
  • heart failure
  • finite element
  • left ventricular
  • catheter ablation