Human Immunodeficiency Virus (HIV)-Negative Men Who Have Sex With Men Have Higher CD8+ T-Cell Counts and Lower CD4+/CD8+ T-Cell Ratios Compared With HIV-Negative Heterosexual Men.
Sebastiaan O VerboeketFerdinand W WitEveline VerheijRosan A van ZoestNeeltje A KootstraMarc van der ValkJan M PrinsMaarten F Schim van der LoeffPeter Reissnull nullPublished in: The Journal of infectious diseases (2022)
These findings suggest that factors other than HIV may, in both PWH and certain HIV-negative MSM, contribute to a low CD4+/CD8+ ratio. Whether this, like in PWH, contributes to comorbidity risk in HIV-negative MSM requires further study.