The Cardiac Sarcomere and Cell Cycle.
Anthony M PettinatoFeria A LadhaJ Travis HinsonPublished in: Current cardiology reports (2022)
This review summarizes known and emerging regulatory mechanisms connecting the human cardiomyocyte sarcomere to cell cycle regulation including structural and signaling mechanisms. Cardiac regeneration could be augmented through targeting the inhibitory effects of the sarcomere on cardiomyocyte proliferation.