Progression-free survival as surrogate endpoint of overall survival in esophageal squamous cell carcinoma: a real-world data and literature-based analysis.

Weiming HanLan WangChen LiJunqiang ChenWencheng ZhangXin WangQingsong PangYidian ZhaoXinchen SunKaixian ZhangGaofeng LiLing LiXueying QiaoMiaoling LiuYadi WangLei DengWenqing WangNan BiTao ZhangWei DengWenjie NiXiao ChangZongmei ZhouJun LiangQinfu FengLvhua WangDongfu ChenJima LvShuchai ZhuChun HanZefen Xiao

Published in: Therapeutic advances in medical oncology (2022)

Three-year PFS may act as a potential surrogate endpoint for 5-year OS. TNM stage was considered a significant prognostic factor for OS, and may represent the optimal prognostic tool to guide clinical decision-making and post-treatment follow-up.

Keyphrases

free survival
prognostic factors
decision making
systematic review
electronic health record
combination therapy
human health
artificial intelligence