Cardiometabolic Phenotyping in Heart Failure: Differences between Patients with Reduced vs. Preserved Ejection Fraction.

Alessio BallettiNicolò De BiaseLavinia Del PuntaFrancesco FilideiSilvia ArmeniaFilippo MasiValerio Di FioreMatteo MazzolaAlessandra BaccaFrank Lloyd DiniStefano TaddeiStefano MasiNicola Riccardo Pugliese

Published in: Diagnostics (Basel, Switzerland) (2023)

In HF patients, HFpEF and HFrEF phenotypes are characterized by different cardiometabolic indices related to distinct inflammatory and congestive pathways. Patients with HFpEF showed an important relationship between inflammatory and cardiometabolic parameters. Conversely, in HFrEF, there is a significant relationship between congestion and inflammation, while cardiometabolism appears not to influence inflammation, instead affecting sympathetic hyperactivation.

Keyphrases

ejection fraction
oxidative stress
aortic stenosis
heart failure
end stage renal disease
newly diagnosed
high throughput
left ventricular
prognostic factors
peritoneal dialysis
atrial fibrillation