High neutrophil-to-lymphocyte ratio (NLR) is associated with treatment failure and death in patients who have melanoma treated with PD-1 inhibitor monotherapy.
Madalyn G NeuwirthJessica R FlynnKatherine S PanageasRichard A FerraroJessica M Sta CruzMichael A PostowDaniel G CoitCharlotte E AriyanPublished in: Cancer (2019)
Elevated baseline NLR and an increased NLR early during treatment are prognostic for TTF and OS in patients who have melanoma treated with PD-1 inhibitor monotherapy. Combined, these biomarkers can widely risk-stratify patients for treatment failure and survival.