Prediction for oxaliplatin-induced liver injury using patient-derived liver organoids.

Kumiko TatsumiHiroshi WadaShinichiro HasegawaKei AsukaiShigenori NagataTomoya EkawaTakashi Akazawa Yu Mizote Shintaro OkumuraRyosuke OkamuraMasayuki OhueKazutaka ObamaHideaki Tahara

Published in: Cancer medicine (2024)

These results suggested that L-OHP-induced liver injury may be caused by mitochondrial oxidative damage. Furthermore, patient-derived liver organoids may be used to assess susceptibility to L-OHP-induced liver injury in individual patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes
patient reported