Molecularly defined extraintestinal pathogenic Escherichia coli status predicts virulence in a murine sepsis model better than does virotype, individual virulence genes, or clonal subset among E. coli ST131 isolates.
Irene MerinoStephen B PorterBrian D JohnstonConnie ClabotsPaul ThurasPatricia Ruiz-GarbajosaRafael CantónJames R JohnsonPublished in: Virulence (2021)
Within ST131 the strongest predictor of experimental virulence was molecularly defined ExPEC status. Clonal subsets seemed to behave differently in the murine sepsis model by country of origin.