Bevacizumab improved prognosis for advanced EGFR-mutant lung adenocarcinoma with brain metastasis receiving cerebral radiotherapy.
Yuanliang ZhouJingchao LiYankang LiGuangchuan DengQi WangHongyue QinJianbin LiZhenxiang LiPublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2024)
In patients with BM from EGFR-mutated NSCLC, cerebral radiotherapy with bevacizumab markedly improved OS. This improvement was more evident after cerebral radiotherapy.
Keyphrases
- small cell lung cancer
- early stage
- subarachnoid hemorrhage
- locally advanced
- cerebral ischemia
- epidermal growth factor receptor
- radiation induced
- radiation therapy
- tyrosine kinase
- metastatic colorectal cancer
- brain injury
- advanced non small cell lung cancer
- squamous cell carcinoma
- rectal cancer
- white matter
- multiple sclerosis
- wild type