Assessment of the link between in utero exposure to 2-aminoanthracene (2AA) and type-1 diabetes (T1D).

Christopher A MaysDaniel A HunterWilson YauWorlanyo E Gato

Published in: Journal of diabetes and metabolic disorders (2017)

It appears that systemic effects of 2AA ingestion were mild in the neonates. Further assessments of pups who lived longer than two weeks could be a useful way to measure the progression and possibly further support our hypothesis that 2AA can lead to systemic effects that are indicative of inducing T1D.

Keyphrases

type diabetes
cardiovascular disease
glycemic control
insulin resistance
low birth weight
metabolic syndrome
gestational age
adipose tissue
preterm birth