Factors predictive of serious infections over time in systemic lupus erythematosus patients: data from a multi-ethnic, multi-national, Latin American lupus cohort.
Victor Román Pimentel-QuirozManuel Francisco Ugarte-GilG B HarveyD WojdylaG J Pons-EstelR QuintanaA EspostoM A GarcíaL J CatoggioM H CardielL A BarileM-C AmigoE I SatoE BonfaE BorbaL T Lavras CostallatO J NeiraL MassardoM Guibert-ToledanoR Chacón-DíazG S AlarcónB A Pons-EstelPublished in: Lupus (2019)
Over time, prednisone doses higher than 15 mg/day, use of methylprednisolone pulses, increase in disease activity and damage accrual were predictive of infections, whereas antimalarial use was protective against them in SLE patients.
Keyphrases
- disease activity
- systemic lupus erythematosus
- end stage renal disease
- rheumatoid arthritis
- ejection fraction
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- oxidative stress
- ankylosing spondylitis
- juvenile idiopathic arthritis
- patient reported outcomes
- electronic health record
- artificial intelligence
- plasmodium falciparum
- patient reported