Association of CSF Biomarkers With Hippocampal-Dependent Memory in Preclinical Alzheimer Disease.
Alexandra N TrelleValerie A CarrEdward N WilsonMichelle S SwarovskiMadison P HuntTyler N TouegTammy T TranDivya ChannappaNicole K CorsoMonica K ThieuManasi JayakumarAyesha NadiadwalaWanjia GuoNatalie J TannerJeffrey D BernsteinCelia P LitovskyScott A GuerinAnna M KhazenzonMarc B HarrisonBrian K RuttGayle K DeutschFrederick T ChinGuido A DavidzonJacob N HallSharon J ShaCarolyn A FredericksKatrin I AndreassonGeoffrey A KerchnerAnthony D WagnerElizabeth C MorminoPublished in: Neurology (2021)
Tests designed to tax hippocampal function are sensitive to subtle individual differences in memory among CU and correlate with early AD-associated biomarker changes in CSF. These tests may offer utility for identifying CU with preclinical AD pathology.