Analysis of the Influence of IL-6 and the Activation of the Jak/Stat3 Pathway in Fibromyalgia.

Ylenia MarinoAlessia ArangiaMarika Cordaro Rosalba Siracusa Ramona D'amico Daniela Impellizzeri Rosalia Crupi Alessio Filippo Peritore Enrico Gugliandolo Roberta Fusco Salvatore Cuzzocrea Rosanna Di Paola

Published in: Biomedicines (2023)

Our study showed that IL-6 plays a crucial role in fibromyalgia by triggering the Jak/STAT3 pathway, leading to an increase in chemokine levels and activating glial cells.

Keyphrases

induced apoptosis
signaling pathway
cell cycle arrest
cell death
spinal cord injury
spinal cord
cell proliferation