A new dimeric alkylresorcinol from the stem barks of Swintonia floribunda (Anacardiaceae).

Phu Hoang DangLinh T T NguyenHue T T NguyenTho H LeTruong N V DoHai X NguyenNghia D LeMai T T NguyenNhan T Nguyen

Published in: Natural product research (2018)

From an EtOAc-soluble fraction of the stem barks of Swintonia floribunda (Anacardiaceae), one new dimeric alkylresorcinol named integracin E (1), together with 4 known compounds (2-5) were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The absolute configuration of 1 was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Compound 1 showed potent tyrosinase inhibitory activity with an IC50 value of 48.2 μM.

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