Body mass index across adulthood and the development of airflow obstruction and emphysema.

Ruth E TretheweyNicole L SpartanoRamachandran S VasanMartin G LarsonGeorge T O'ConnorDale W EsligerEmily S PetherickMichael C Steiner

Published in: Chronic respiratory disease (2022)

Mean BMI is lower throughout adulthood in AO and LLD participants. Lower BMI is associated with a steeper decline in the ratio of FEV<sub>1</sub>/FVC. These findings suggest body mass may precede and potentially have a role in the development of COPD lung pathophysiology.

Keyphrases

body mass index
chronic obstructive pulmonary disease
weight gain
lung function
depressive symptoms
physical activity
early life
weight loss