Maternal and neonatal antibody levels on pertussis vaccination in pregnant women on immune-modulating therapy for rheumatic disease.

Nafise GhalandariMaarten M ImminkEsther RöderPatricia C J Bruijning-VerhagenHieronymus T W SmeeleHubertina CrijnsNicoline A T van der MaasMireille N BekkerElisabeth A M SandersRadboud J E M Dolhain

Published in: RMD open (2023)

These preliminary data indicate no major differences in IgG antibody levels on maternal Tdap vaccination in pregnant women with or without immune-modulating treatment, although our findings suggest that TNFis during pregnancy induce lower maternal anti-pertussis-specific protective antibody levels in newborns.

Keyphrases

pregnant women
pregnancy outcomes
birth weight
signaling pathway
electronic health record
machine learning
body mass index
big data
preterm infants
combination therapy
weight loss
data analysis