Family History of Prostate and Breast Cancer Integrated with a Polygenic Risk Score Identifies Men at Highest Risk of Dying from Prostate Cancer before Age 75 Years.

Anna Plym Yiwen Zhang Konrad H Stopsack Yon Ho Jee Fredrik Wiklund Adam S Kibel Peter Kraft Edward L Giovannucci Kathryn L Penney Lorelei A Mucci

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Our study shows that prostate cancer risk stratification on the basis of family history and inherited polygenic risk can identify men at highest risk of dying from prostate cancer before age 75 years.

Keyphrases

prostate cancer
radical prostatectomy
palliative care
middle aged
genome wide