Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development.

Juan LiuZongjian TanJun HeTingting JinYuanyuan HanLi HuShengwen Huang

Published in: Journal of assisted reproduction and genetics (2021)

Our findings expand the mutational spectrum of PADI6 and TLE6 associated with embryonic developmental arrest and deepen our understanding of the genetic causes of infertility with recurrent ART failure.

Keyphrases

genome wide
cell cycle
polycystic ovary syndrome
copy number
antiretroviral therapy
cell proliferation
genome wide identification
type diabetes
adipose tissue
metabolic syndrome
genome wide analysis