FAP is a prognostic marker, but not a viable therapeutic target for clinical translation in HNSCC.
Jie LiuYeling OuyangZijin XiaWenhao MaiHongrui SongFang ZhouLichun ShenKaiting ChenXiaochen LiShi-Min ZhuangJing LiaoPublished in: Cellular oncology (Dordrecht) (2023)
CAFs have attracted increasing attention for their role in cancer, the feasibility and efficacy of FAP-targeting therapies for HNSCC remain doubtful.