Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct.

Roland H StimsonAnna J AndersonLynne E RamageDavid P MacfarlaneAndrew C de BeauxDamian J MoleRuth AndrewBrian R Walker

Published in: Diabetes, obesity & metabolism (2017)

The acute lipolytic effects of cortisol require supraphysiological concentrations, are dependent on insulin and adrenaline and are observed only in subcutaneous adipose tissue. The resistance of visceral adipose tissue to cortisol's lipolytic effects may contribute to the central fat accumulation observed with chronic glucocorticoid excess.

Keyphrases

adipose tissue
insulin resistance
liver failure
respiratory failure
high fat diet
drug induced
type diabetes
aortic dissection
hepatitis b virus
intensive care unit
metabolic syndrome
skeletal muscle
glycemic control
mechanical ventilation
acute respiratory distress syndrome