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Oscillatory mechanisms of intrinsic human brain networks.

Youjing LuoXianghong MengGuangyu ZhouJiali ZhouYue-Jia LuoHui AiChristina ZelanoFuyong ChenPengfei Xu
Published in: NeuroImage (2024)
Non-invasive neuroimaging has revealed specific network-based resting-state dynamics in the human brain, yet the underlying neurophysiological mechanism remains unclear. We employed intracranial electroencephalography to characterize local field potentials within the default mode network (DMN), frontoparietal network (FPN), and salience network (SN) in 42 participants. We identified stronger within-network phase coherence at low frequencies (θ and α band) within the DMN, and at high frequencies (γ band) within the FPN. Hidden Markov modeling indicated that the DMN exhibited preferential low frequency phase coupling. Phase-amplitude coupling (PAC) analysis revealed that the low-frequency phase in the DMN modulated the high-frequency amplitude envelopes of the FPN, suggesting frequency-dependent characterizations of intrinsic brain networks at rest. These findings provide intracranial electrophysiological evidence in support of the network model for intrinsic organization of human brain and shed light on the way brain networks communicate at rest.
Keyphrases
  • resting state
  • functional connectivity
  • high frequency
  • transcranial magnetic stimulation
  • room temperature
  • network analysis
  • white matter
  • brain injury
  • optic nerve
  • subarachnoid hemorrhage