Structure-specific rigid dose accumulation dosimetric analysis of ablative stereotactic MRI-guided adaptive radiation therapy in ultracentral lung lesions.
John Michael BryantRuben J Cruz-ChamorroAlberic GanCasey LiveringhouseJoseph WeygandAnn NguyenEmily KeitMaria L SandovalAustin J SimBradford A PerezThomas J DillingGage RedlerJacqueline AndreozziLouis NardellaArash O NaghaviVladimir FeygelmanKujtim LatifiStephen A RosenbergPublished in: Communications medicine (2024)
SMART has dosimetric advantages and excellent clinical outcomes for ultracentral lung tumors. Daily plan adaptation reliably improves target coverage while simultaneously reducing doses to the proximal airways. These results further characterize the therapeutic window improvements for SMART. Structure-specific rigid dose accumulation dosimetric analysis provides insights that elucidate the dosimetric advantages of SMART more so than per fractional analysis alone.