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Value of total tumor load as a clinical and pathological factor in the prognosis of breast cancer patients receiving neoadjuvant treatment. Comparison of three populations with three different surgical approaches: NEOVATTL Pro 3 Study.

María Dolores Martín-SalvagoMagdalena SanchoM Ángeles López-GarcíaAlicia Cano JiménezAna Pérez-LuqueLina AlfaroBegoña Vieites
Published in: Breast cancer research and treatment (2023)
No significant differences in DFS were observed between three centers with different surgical approaches to ALND based on different TTL cut-offs in patients with BC after NAST. These results suggest that restricting ALND to those patients with TTL ≥ 15,000 copies/μL is a reliable approximation, avoiding unnecessary morbidities caused by ALND.
Keyphrases
  • rectal cancer
  • locally advanced
  • young adults
  • radiation therapy
  • squamous cell carcinoma
  • combination therapy
  • genetic diversity
  • clinical evaluation