The natural product trienomycin A is a STAT3 pathway inhibitor that exhibits potent in vitro and in vivo efficacy against pancreatic cancer.

Qiu-Rui HeJiang-Jiang TangYao LiuZhi-Fan ChenYu-Xi LiuHuang ChenDing LiZheng-Fang YiJin-Ming Gao

Published in: British journal of pharmacology (2021)

Trienomycin A exerted anti-neoplastic activity by suppressing STAT3 activation in pancreatic cancer. This natural product could be a novel therapeutic candidate for pancreatic cancer.

Keyphrases

cell proliferation
anti inflammatory