Early retinal neurovascular impairment in patients with diabetes without clinically detectable retinopathy.
Yunkao ZengDan CaoHonghua YuDawei YangXuenan ZhuangYunyan HuJuan LiJing YangQiaowei WuBaoyi LiuLiang ZhangPublished in: The British journal of ophthalmology (2019)
Functional and structural impairments have already started in diabetic retina even in the absence of visible retinal lesions. Subtle microvascular abnormalities rather than ganglion cell loss might be associated with early functional changes in NDR patients. Poor control of blood glucose was associated with delayed implicit time of flicker ERG in preclinical diabetic retinopathy.
Keyphrases
- diabetic retinopathy
- blood glucose
- optical coherence tomography
- end stage renal disease
- optic nerve
- newly diagnosed
- ejection fraction
- chronic kidney disease
- type diabetes
- cell therapy
- glycemic control
- prognostic factors
- peritoneal dialysis
- single cell
- adipose tissue
- mesenchymal stem cells
- patient reported outcomes
- wound healing
- weight loss
- bone marrow