Optically assembled droplet interface bilayer (OptiDIB) networks from cell-sized microdroplets.

Mark S Friddin Guido BolognesiYuval ElaniNicholas J BrooksRobert V LawJohn M SeddonMark A A NeilOscar Ces

Published in: Soft matter (2018)

We report a new platform technology to systematically assemble droplet interface bilayer (DIB) networks in user-defined 3D architectures from cell-sized droplets using optical tweezers. Our OptiDIB platform is the first demonstration of optical trapping to precisely construct 3D DIB networks, paving the way for the development of a new generation of modular bio-systems.

Keyphrases

single cell
high throughput
cell therapy
high resolution
high speed
stem cells
mass spectrometry
mesenchymal stem cells