HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral obstruction model.
Bodokhsuren TsogbadrakhKyung Don JuJinho LeeMiyeun HanJunga KohYeonsil YuHajeong LeeKyung-Sang YuYun Kyu OhHyo Jin KimCurie AhnKook-Hwan OhPublished in: PloS one (2018)
Taken together, the above findings suggest that HL156A, a novel AMPK activator, ameliorates renal fibrosis in vivo and in vitro.