Variations in maternal adenylate cyclase genes are associated with congenital Zika syndrome in a cohort from Northeast, Brazil.

Á D RossiF R FauczA MeloP PezzutoG S de AzevedoB L F Schamber-ReisJ S TavaresJ J MattapallilA TanuriR S AguiarCynthia Chester CardosoC A Stratakis

Published in: Journal of internal medicine (2018)

These results suggest that maternal ADCY genes contribute to ZIKV pathogenicity and influence the outcome of CZS, being promising candidates for further replication studies and functional analysis.

Keyphrases

zika virus
genome wide
birth weight
pregnancy outcomes
genome wide identification
bioinformatics analysis
dna methylation
gene expression
pregnant women
biofilm formation
escherichia coli
cystic fibrosis