Tumor Marker-Based Definition of the Transarterial Chemoembolization-Refractoriness in Intermediate-Stage Hepatocellular Carcinoma: A Multi-Cohort Study.
Jun Sik YoonDong Hyun SinnJeong-Hoon LeeHwi Young KimCheol-Hyung LeeSun Woong KimHyo Young LeeJoon Yeul NamYoung ChangYun Bin LeeEun-Ju ChoSu Jong YuHyo-Cheol KimJin Wook ChungYun Joon KimJung-Hwan YoonPublished in: Cancers (2019)
The ΔMoRAL after the first TACE, a simple and objective index, provides refined prognostication for patients with intermediate-stage HCC. Proceeding to a second TACE may not provide additional survival benefits in cases of a MoRAL-increase after the first TACE in patients with a high baseline MoRAL score (≥89.5), who might be candidates for systemic therapy.