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Conjugated polymers for biomedical applications.

Hongrui LinHaotian BaiZhiwen YangQi ShenMingyu LiYiming HuangFengting LvJianwu Wang
Published in: Chemical communications (Cambridge, England) (2022)
Conjugated polymers (CPs) are a series of organic semiconductor materials with large π-conjugated backbones and delocalized electronic structures. Due to their specific photophysical properties and photoelectric effects, plenty of CPs with varied chemical structures and functions are quickly evolving in the diverse biomedical field, such as fluorescence imaging, photodynamic therapy, photothermal therapy, etc. In addition, the functionalized side chains of CPs could contribute to the expected water-solubility, biocompatibility, biological response, etc. CPs can also be prepared into nanoparticles for acquiring controllable particle size and dispersion through the common synthesis procedure. In this review, we focus on the latest developments of CPs in biotherapy, biological regulation, biological response and bioprinting applications. The major challenges and outlooks of CPs for applications in the biomedical field are also discussed.
Keyphrases
  • photodynamic therapy
  • fluorescence imaging
  • high resolution
  • minimally invasive
  • room temperature
  • mass spectrometry
  • ionic liquid