Prevalence and Detection of Sexually Transmitted Cases of Laryngeal Carcinoma.
Mohammad Abdulhameed Al-QudahAla'a Fuad Al-ShaikhHusam Kamel HaddadMohammad Abdelatif ElhassanOsman Basheir ElhassanMelad Nabeel DababnehAnas Wasef ZaitounNawwaf Saleh Al GhamdiBara'a Yousef Al-NajjarPublished in: Head and neck pathology (2020)
The prevalence of HPV-positive LSCC was lower than previously stated in the literature. HPV-16 was the most commonly detected subtype, in concordance with the findings of multiple other studies. HPV-positive LSCC trended with higher histologic grade. P16 and cyclin E immunohistochemical stains were of limited use in identifying HPV in LSCC. In contrast, cyclin B had a high sensitivity which could be used to rule out HPV in LSCC.