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Vaccination Recommendations in Solid Organ Transplant Adult Candidates and Recipients.

Mauro ViganòMarta BerettaMarta LeporeRaffaele AbeteSimone Vasilij BenattiMaria Vittoria GrassiniStefania CamagniGreta ChiodiniSimone VargiuClaudia VittoriMarco IachiniAmedeo TerziFlavia NeriDomenico PinelliValeria CasottiFederico RaimondiPiero RuggenentiMarco RizziMichele ColledanStefano Fagiuoli
Published in: Vaccines (2023)
Prevention of infections is crucial in solid organ transplant (SOT) candidates and recipients. These patients are exposed to an increased infectious risk due to previous organ insufficiency and to pharmacologic immunosuppression. Besides infectious-related morbidity and mortality, this vulnerable group of patients is also exposed to the risk of acute decompensation and organ rejection or failure in the pre- and post-transplant period, respectively, since antimicrobial treatments are less effective than in the immunocompetent patients. Vaccination represents a major preventive measure against specific infectious risks in this population but as responses to vaccines are reduced, especially in the early post-transplant period or after treatment for rejection, an optimal vaccination status should be obtained prior to transplantation whenever possible. This review reports the currently available data on the indications and protocols of vaccination in SOT adult candidates and recipients.
Keyphrases
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  • prognostic factors
  • peritoneal dialysis
  • patient reported outcomes
  • mesenchymal stem cells
  • hepatitis b virus
  • childhood cancer