Novel long-range regulatory mechanisms controlling PKD2 gene expression.

Stéphanie MoisanStéphanie LevonEmilie Cornec-Le GallYannick Le MeurMarie-Pierre AudrézetJosée DostieClaude Férec

Published in: BMC genomics (2018)

Finally, through alignment of CCCTC-binding factor (CTCF) sites, we suggest that these novel enhancer elements are brought to the PKD2 promoter by chromatin looping via the recruitment of CTCF.

Keyphrases

gene expression
transcription factor
polycystic kidney disease
dna binding
dna methylation
binding protein
genome wide
oxidative stress