METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells.

Haiyun LuoWenjing LiuYanli ZhangYeqing YangXiao JiangShiqing WuLong-Quan Shao

Published in: Stem cell research & therapy (2021)

These results revealed m6A methylated hallmarks in DPSCs and a regulatory role of METTL3 in cell cycle control. Our study shed light on therapeutic approaches in vital pulp therapy and served new insight into stem cell-based tissue engineering.

Keyphrases

cell cycle
stem cells
tissue engineering
cell proliferation
cell therapy
single cell
mesenchymal stem cells
bone marrow
replacement therapy