[Influence of CNV vascular morphology in exudative age-related macular degeneration on development of visual acuity and need for anti-VEGF therapy after 1 year].
Henrik FaatzMarie-Louise GunnemannKai RothausMarius BookMatthias GutfleischAlbrecht LommatzschDaniel PauleikhoffPublished in: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft (2021)
The results show that a mathematical quantification of the CNV in nAMD is possible using OCT‑A. This analysis confirmed again that the size of the CNV (area and total vessel length) is decisive for the prognosis of visual acuity. It also shows that a larger flow value as a sign of a well-differentiated CNV is associated with a better functional prognosis. The number of IVOMs required, however, depends primarily on the composition of the CNV (flow value and vascular caliber). More precise imaging and larger examination cohorts could possibly reveal further relevant biomarkers.