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Long-term oral exposure to safe dose of bisphenol A in association with high-fat diet stimulate the prostatic lesions in a rodent model for prostate cancer.

Camila H FacinaSilvana G P CamposBianca F GonçalvesRejane M GóesPatricia S L VilamaiorSebastião Roberto Taboga
Published in: The Prostate (2017)
The results indicated that the methodology used was effective in generating metabolic changes, which directly compromised prostatic homeostasis. Diet and BPA appear to modulate the activation of the AR pathway and thereby optimize tumor establishment in the gerbil prostate.
Keyphrases
  • high fat diet
  • prostate cancer
  • radical prostatectomy
  • benign prostatic hyperplasia
  • insulin resistance
  • adipose tissue
  • physical activity
  • weight loss
  • type diabetes
  • skeletal muscle
  • subarachnoid hemorrhage