MiR-200c-3p as a novel genetic marker and therapeutic tool for alopecia areata.
Ahmed Ibrahim AbdElneamMohammed Saleh Al-DhubaibiSaleh Salem BahajGhadah I ALHetheliPublished in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
We were able to identify the influence of miR-200c-3p on both PLCG1 and RPS6KP1 genes which in turn regulate the EGFR tyrosine kinases resistance pathway that displayed the most substantial increase in activity. Our outcomes shed light on the era of the potential theranostic role of this innovative miRNA in AA.
Keyphrases
- cell proliferation
- long non coding rna
- long noncoding rna
- genome wide
- small cell lung cancer
- epidermal growth factor receptor
- photodynamic therapy
- fluorescent probe
- sensitive detection
- living cells
- fluorescence imaging
- type diabetes
- risk assessment
- human health
- transcription factor
- glycemic control
- weight loss
- quantum dots