Covarying patterns of white matter lesions and cortical atrophy predict progression in early MS.

Muthuraman MuthuramanVinzenz FleischerJulia KrothDumitru CiolacAngela RadetzNabin KoiralaGabriel Gonzalez-EscamillaHeinz WiendlSven G MeuthFrauke ZippSergiu Groppa

Published in: Neurology(R) neuroimmunology & neuroinflammation (2020)

These findings highlight the role of distinct spatial distribution of cortical atrophy and WM lesions predicting disability. The cerebellar involvement is shown as a key determinant of rapid clinical deterioration.

Keyphrases

white matter
multiple sclerosis
mass spectrometry
ms ms
sensitive detection