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Design, Docking, Characterisation, and Synthesis of Pyrimidine Derivatives for Antidepressant Activity.

Ashwini JadhavSunil G ShingadePrachita Gauns DessaiBheemanagouda S BiradarShivalingrao MamleDesai
Published in: Current drug discovery technologies (2023)
Compound 24 showed the highest MolDock score as well as found to be the most potent antidepressant agent.
Keyphrases
  • major depressive disorder
  • molecular dynamics
  • molecular dynamics simulations
  • bipolar disorder
  • protein protein
  • anti inflammatory
  • small molecule
  • structure activity relationship