Genetic and pharmacological inactivation of astroglial connexin 43 differentially influences the acute response of antidepressant and anxiolytic drugs.

Benjamin PortalSarah DelcourteRenaud RoveraCamille LejardsSebastien BullichCécile E Malnou Nasser Haddjeri Nicole Déglon Bruno P Guiard

Published in: Acta physiologica (Oxford, England) (2020)

Collectively, these data pave the way to the development of potentiating strategies in the field of psychiatry based on the modulation of astroglial Cx43.

Keyphrases

liver failure
drug induced
major depressive disorder
respiratory failure
electronic health record
genome wide
big data
copy number
machine learning
intensive care unit
bipolar disorder
dna methylation
extracorporeal membrane oxygenation
deep learning
mechanical ventilation